Human Dermal Lymphatic Endothelial Cells (HDLEC)

Producer

Primary Human Dermal Lymphatic Endothelial Cells (HDLEC) are a subpopulation of the Human Dermal Endothelial Cells. They are isolated from the dermis of juvenile foreskin and adult skin (different locations) from a single donor.
(Human Dermal Blood Endothelial Cells (HDBEC) from the same donor are available on request.)
The cells are routinely analyzed by flow cytometric analysis and immunofluorescent staining:
> 95% of the cells are CD31 positive and podoplanin positive. In addition, the cells stain positive for Prox-1.
Lymphatic vessels transport excess fluids from tissues to the circulatory system and are a major component of the immune system. The transported fluid is nearly cell free. The vessels are highly permeable, because they lack a continuous basal membrane. Lymphatic endothelial cells are involved in pathological alterations of the lymphatic system. During tumor lymphangiogenesis, the lymphatic endothelial cells build new vessels that infiltrate tumors, attract tumor cells, and induce tumor cell metastasis.

 
 
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Article No. Description Cell Type Donor Preparation Unit/Case
Cells
On Stock
C-12216-PRO HDLEC juvenile foreskin, cryopreserved HDLEC juvenile foreskin, cryopreserved Human Dermal Lymphatic Endothelial Cells   cryopreserved 500000 Delivery time
C-12217-PRO Human Dermal Lymphatic Endothelial Cells Human Dermal Lymphatic Endothelial Cells (HDLEC) adult donor, cryopreserved Human Dermal Lymphatic Endothelial Cells adult cryopreserved 500000 Delivery time
C-12218-PRO HDLEC juvenile foreskin, proliferating HDLEC juvenile foreskin, proliferating Human Dermal Lymphatic Endothelial Cells   proliferating 500000 Delivery time
C-12219-PRO Human Dermal Lymphatic Endothelial Cells Human Dermal Lymphatic Endothelial Cells (HDLEC) adult donor, proliferating Human Dermal Lymphatic Endothelial Cells adult proliferating 500000 Delivery time
C-14020-PRO HDLEC Pellet, in RNAlater HDLEC Pellet, in RNAlater Normal Human Dermal Lymphatic Endothelial Cells   Pellet 1000000 Delivery time
C-14021-PRO HDLEC adult Pellet, in RNAlater HDLEC adult Pellet, in RNAlater Normal Human Dermal Lymphatic Endothelial Cells adult Pellet 1000000 Delivery time
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